A Stigmasterol Containing n-hexane Fraction of Rauvolfia serpentina Methanolic Extract Shows Tissue-Specific Variation of Biocidal and Antioxidant Activities. Issue 1 (2nd January 2016)

• Record Type: Journal Article
• Authors: Dey, Abhijit; Mukherjee, Souryadeep; De, Arijit; Pandey, Devendra Kumar
• Is Part Of: Journal of herbs, spices & medicinal plants. Volume 22:Issue 1(2016)
• Page Start: 81
• Page End: 91
• Publication Date: 2016-01-02
• Subjects: HPTLC -- densitometry -- antibacterial -- antioxidant; Medicinal plants -- Periodicals; Herbs -- Periodicals; Spices -- Periodicals; 581.63
• DOI: 10.1080/10496475.2015.1042617
• Languages: English
• ISSNs: 1049-6475

Abstract

Abstract : Tissue-specific variation of stigmasterol in Rauvolfia serpentina and the corresponding biocidal and antioxidant activities of the methanol extract were measured using high-performance thin-layer chromatography. Stigmasterol had the highest concentration in the roots. The highest radical scavenging activity was seen in the root extract (60.94%) at 1 mg.mL −1 DPPH gradient; highest total phenolics content in 1 mg.mL −1 of the root extract was 67 μg of Gallic acid equivalent mg −1 d.w.; highest flavonoids present in the extract was 275 μg of Quercetin equivalent mg −1 d.w. The antibacterial activity was correlated to the amount of stigmasterol, total phenolics, total flavonoids, and antioxidants present in the plant parts.