Rhodium-catalyzed selective oxidative coupling of 7-azaindoles. Issue 20 (19th May 2016)

• Record Type: Journal Article
• Authors: Li, Shuai-Shuai; Wang, Cheng-Qi; Li, Wei-Huan; Zhang, Xiao-Mei; Dong, Lin
• Is Part Of: Tetrahedron. Volume 72:Issue 20(2016)
• Page Start: 2581
• Page End: 2586
• Publication Date: 2016-05-19
• Subjects: 7-Azaindole -- Rhodium -- C–H bonds activation -- Olefination -- N-naphthylazole; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2016.03.092
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: An efficient rhodium(III)-catalyzed C–H activation has been developed by using 7-azaindole as a directing group. A wide variety of olefinated 7-azaindole derivatives and N -naphthylazole derivatives have been selectively formed in moderate to excellent yields when alkenes or alkynes act as the C–H coupling partner. Graphical abstract: An efficient rhodium(III)-catalyzed C–H activation has been developed by using 7-azaindole as a directing group. A wide variety of olefinated 7-azaindole derivatives and N -naphthylazole derivatives have been selectively formed in moderate to excellent yields when alkenes or alkynes act as the C–H coupling partner.