Novel Ferrocenyl Linked Pyrazoline Analogs as Potent Antiamoebic Agents. (16th April 2015)
- Record Type:
- Journal Article
- Title:
- Novel Ferrocenyl Linked Pyrazoline Analogs as Potent Antiamoebic Agents. (16th April 2015)
- Main Title:
- Novel Ferrocenyl Linked Pyrazoline Analogs as Potent Antiamoebic Agents
- Authors:
- Parveen, Humaira
Mukhtar, Sayeed
Azam, Amir - Abstract:
- Abstract : Some novel ferrocenyl linked pyrazoline analogs were synthesized, well characterized, and evaluated for in vitro antiamoebic activity against HM1 : IMSS strain of Entamoeba histolytica . Most of the compounds exhibited higher antiamoebic activity with the IC50 value in the range of 0.12–1.20 μM, than the reference drug metronidazole, (IC50 value of 1.78 μM). Compound9 showed the most promising antiamoebic activity (IC50 = 0.12 μM), concluding that these compounds hold immense potential to be employed as new antiamoebic agents. Also, being novel, they can be a solution to the increasing resistance that has posed a major problem globally. Abstract :
- Is Part Of:
- Journal of heterocyclic chemistry. Volume 53:Number 2(2016:Mar.)
- Journal:
- Journal of heterocyclic chemistry
- Issue:
- Volume 53:Number 2(2016:Mar.)
- Issue Display:
- Volume 53, Issue 2 (2016)
- Year:
- 2016
- Volume:
- 53
- Issue:
- 2
- Issue Sort Value:
- 2016-0053-0002-0000
- Page Start:
- 473
- Page End:
- 478
- Publication Date:
- 2015-04-16
- Subjects:
- Heterocyclic compounds -- Periodicals
547.59 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/jhet.2427 ↗
- Languages:
- English
- ISSNs:
- 0022-152X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4998.200000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1331.xml