A plasmonic chip-based bio/chemical hybrid sensing system for the highly sensitive detection of C-reactive protein. Issue 20 (10th December 2015)

• Record Type: Journal Article
• Authors: Matsuura, Ryo; Tawa, Keiko; Kitayama, Yukiya; Takeuchi, Toshifumi
• Is Part Of: Chemical communications. Volume 52:Issue 20(2016)
• Page Start: 3883
• Page End: 3886
• Publication Date: 2015-12-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc07868g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A synthetic polymer ligand-grafted plasmonic chip was fabricated and demonstrated a highly sensitive detection of C-reactive protein (CRP) by grating-coupled surface plasmon field-enhanced fluorescence. Abstract : A synthetic polymer ligand-grafted plasmonic chip was fabricated and demonstrated a highly sensitive detection of C-reactive protein (CRP) by grating-coupled surface plasmon field-enhanced fluorescence. Poly(2-methacryloyloxyethyl-phosphorylcholine) was used as a CRP-specific polymer ligand layer and was grafted onto the plasmonic chip using surface-initiated controlled/living radical polymerization (limit of detection: ca. 10 pM).