Triazine‐Triazole Conjugates as Potent Ligands for Cu–Catalyzed Sonogashira Reaction. Issue 3 (3rd March 2016)

• Record Type: Journal Article
• Authors: Wang, Zhenhua; Wang, Xiu; Sun, Huaming; Zhu, Zhuangli; Zhang, Guofang; Zhang, Weiqiang; Gao, Ziwei
• Is Part Of: ChemistrySelect. Volume 1:Issue 3(2016)
• Page Start: 391
• Page End: 395
• Publication Date: 2016-03-03
• Subjects: N ligands -- CuSO4⋅5H2O -- Sonogashira reaction -- decarboxylative coupling -- copper catalysis; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201600113
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: Triazine Triazole conjugates (TT ) were developed as efficient ligand system for CuSO4 ⋅5H2 O catalyzed Sonogashira and decarboxylative cross‐coupling reaction. This new protocol showed good compatibility with a broad range of substitutents and afforded moderate to excellent yields.TT ligands are rapid constructed and highly modular electronically and sterically. Abstract : CuSO4 ⋅5H2 O/L1 system was developed for Sonogashira and decarboxylative cross‐coupling reaction. This new protocol showed good compatibility with a broad range of substituents and afforded moderate to excellent yields. TT ligands are rapid construction structures, highly modular, easily electronically and sterically modified. It was also worth noted that both Cu(I) and Cu(II) salts were significantly accelerated by TT ligands for the cross‐coupling reaction.