Non cystic fibrosis bronchiectasis. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: Kansra, Sonal; Bradbrook, Benjamin
• Is Part Of: Paediatrics and child health. Volume 25:Issue 4(2015)
• Page Start: 179
• Page End: 181
• Publication Date: 2015-04
• Subjects: airway clearance techniques -- HRCT -- macrolides -- non CF bronchiectasis -- vicious cycle hypothesis; Pediatrics -- Periodicals; Pediatrics -- Periodicals; Pédiatrie -- Périodiques; 618.920005
• DOI: 10.1016/j.paed.2014.12.002
• Languages: English
• ISSNs: 1751-7222

Abstract

Abstract: Bronchiectasis unrelated to cystic fibrosis is an important cause of respiratory morbidity and mortality in children globally. A vicious cycle of infection, muco-ciliary impairment and chronic inflammation leads to structural damage and irreversible dilatation of bronchi. A wide range of underlying conditions can lead to bronchiectasis and it is vital to investigate these children thoroughly. Management should be proactive and aim at minimizing daily symptoms, maximizing quality of life and preventing decline in lung functions. Central to management of bronchiectasis is identification and treatment of the underlying condition. Prompt treatment of exacerbations with antimicrobials and limiting further damage by strategies like immunization are other important aspects. Macrolides may help cut down exacerbations and reduce airway inflammation.