A new acetylated spirostanol saponin and other constituents from the rhizomes of Dioscorea althaeoides R. Knuth (Dioscoreaceae). (April 2016)

• Record Type: Journal Article
• Authors: Li, Xuejiao; Jing, Songsong; Man, Shuli; Li, Xia; Zhao, Chengcheng; Wang, Ying; Gao, Wenyuan
• Is Part Of: Biochemical systematics and ecology. Volume 65(2016)
• Page Start: 17
• Page End: 22
• Publication Date: 2016-04
• Subjects: Dioscorea althaeoides -- Dioscin-6′-O-acetate -- Spirostanol saponins -- Furostanol saponins -- Diarylheptanoid -- Sterols; Chemotaxonomy -- Periodicals; Biochemical variation -- Periodicals; Ecology -- Periodicals; Biochemistry -- Periodicals; Ecology -- Periodicals; Chimiotaxinomie -- Périodiques; Variation biochimique -- Périodiques; Écologie -- Périodiques; 578.012
• DOI: 10.1016/j.bse.2016.01.010
• Languages: English
• ISSNs: 0305-1978

Abstract

Abstract: A new acetylated spirostanol saponin (7 ), dioscin-6′- O -acetate, was isolated from the rhizomes of Dioscorea althaeoides R. Knuth (Dioscoreaceae), together with fourteen known compounds, including three spirostanol saponins (1 –2, 6 ), three furostanol saponins (10 –12 ), one diarylheptanoid (3 ), three sterols (4–5, 9 ), three aliphatic acids (8, 13 –14 ) and one aliphatic alkane (15 ). Their structures were established by extensive 1D- and 2D- NMR (DEPT, 1 H– 1 H COSY, HSQC, HMBC and NOESY) experiments in conjunction with IR and HRESI/TOF-MS data, as well as the results of acid hydrolysis. The compounds (3 –8, 10 –15 ) were isolated from this species for the first time. The chemotaxonomic significance of these compounds was also discussed Highlights: A new acetylated spirostanol saponin and 14 known compounds, was isolated. The structure of the new saponin was firstly elucidated. The chemotaxonomic significance of the compounds was discussed.