Non-opioid analgesics: Novel approaches to perioperative analgesia for major spine surgery. Issue 1 (March 2016)

• Record Type: Journal Article
• Authors: Dunn, Lauren K.; Durieux, Marcel E.; Nemergut, Edward C.
• Is Part Of: Best practice & research. Volume 30:Issue 1(2016)
• Page Start: 79
• Page End: 89
• Publication Date: 2016-03
• Subjects: dexmedetomidine -- gabapentin -- ketamine -- multimodal pain management -- paracetamol -- perioperative pain -- postoperative pain -- pregabalin; ITM intrathecal morphine -- NMDA N-methyl d-aspartate -- NRS numeric rating system -- PCA patient-controlled analgesia -- VAS visual analog scale; Anesthesiology -- Periodicals; Anesthesia -- Periodicals; Anesthesia -- Periodicals; Anesthetics -- Periodicals; Anesthesia; Anesthesiology; Periodicals; 617.9605
• DOI: 10.1016/j.bpa.2015.11.002
• Languages: English
• ISSNs: 1521-6869

Abstract

Abstract : Perioperative pain management is a significant challenge following major spine surgery. Many pathways contribute to perioperative pain, including nociceptive, inflammatory, and neuropathic sources. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies have been increasingly used as part of a multimodal analgesic regimen to provide improved pain control while minimizing opioid-related side effects. Here we review the evidence supporting the use of novel analgesic approaches as an alternative to intravenous opioids for major spine surgery.