ChemInform Abstract: Synthesis of Chiral 3‐Substituted 1, 3, 4, 5‐Tetrahydro‐1, 4‐benzodiazepin‐2‐ones via a Domino Copper‐Catalyzed SN2/Coupling Reaction. Issue 15 (24th March 2016)

• Record Type: Journal Article
• Authors: Lu, Dongming; Ma, Chang; Yuan, Shuai; Zhou, Lihong; Zeng, Qingle
• Is Part Of: ChemInform. Volume 47:Issue 15(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-03-24
• Subjects: diazepine derivatives -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) -- ring closure reactions, annulation reactions -- cascade reactions, domino reactions, tandem reactions; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201615178
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: First, the reaction of 2‐iodobenzyl bromide (Ia) with various (S)‐amino acids is investigated to produce the desired benzodiazepine structures.