Enantioselective iridium-catalyzed hydrogenation of β, β-disubstituted nitroalkenes. Issue 26 (10th March 2016)

• Record Type: Journal Article
• Authors: Yu, Yan-Bo; Cheng, Lei; Li, Yi-Pan; Fu, Yue; Zhu, Shou-Fei; Zhou, Qi-Lin
• Is Part Of: Chemical communications. Volume 52:Issue 26(2016)
• Page Start: 4812
• Page End: 4815
• Publication Date: 2016-03-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc01273f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The highly enantioselective hydrogenation of both β-aryl-β-methyl-nitroalkenes and β-alkyl-β-methyl-nitroalkenes was realized by using a novel chiral spiro iridium catalyst. Abstract : An iridium complex with a newly prepared chiral spiro amino-phosphine ligand efficiently catalyzed the hydrogenation of both β-aryl-β-methyl-nitroalkenes and β-alkyl-β-methyl-nitroalkenes to the corresponding saturated nitroalkanes, which represents the first report of a chiral catalyst that exhibits high enantioselectivity for the challenging hydrogenation of β, β-dialkyl-nitroalkenes.