A simplified method of walking track analysis to assess short-term locomotor recovery after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs. (April 2016)

• Record Type: Journal Article
• Authors: Song, R.B.; Oldach, M.S.; Basso, D.M.; da Costa, R.C.; Fisher, L.C.; Mo, X.; Moore, S.A.
• Is Part Of: Veterinary journal. Volume 210(2016)
• Page Start: 61
• Page End: 67
• Publication Date: 2016-04
• Subjects: Spinal cord injury -- Intervertebral disc disease -- Dog -- Locomotor recovery -- Outcome assessment; Veterinary medicine -- Periodicals; 636
• DOI: 10.1016/j.tvjl.2016.01.013
• Languages: English
• ISSNs: 1090-0233

Abstract

Highlights: Stride length (SL) and base of support (BS) were compared in normal and SCI-affected dogs. SL and BS were consistent across three testing sessions in normal dogs. SL was shorter in pelvic and thoracic limbs for SCI-affected dogs at 3, 10, and 30 days. BS in the thoracic limbs was wider in SCI-affected dogs at 3 and 30 days. Pelvic limb BS did not differ between normal and SCI-affected dogs at any time point. Abstract: The purpose of this study was to evaluate a simplified method of walking track analysis to assess treatment outcome in canine spinal cord injury. Measurements of stride length (SL) and base of support (BS) were made using a 'finger painting' technique for footprint analysis in all limbs of 20 normal dogs and 27 dogs with 28 episodes of acute thoracolumbar spinal cord injury (SCI) caused by spontaneous intervertebral disc extrusion. Measurements were determined at three separate time points in normal dogs and on days 3, 10 and 30 following decompressive surgery in dogs with SCI. Values for SL, BS and coefficient of variance (COV) for each parameter were compared between groups at each time point. Mean SL was significantly shorter in all four limbs of SCI-affected dogs at days 3, 10, and 30 compared to normal dogs. SL gradually increased toward normal in the 30 days following surgery. As measured by this technique, the COV-SL was significantly higher in SCI-affected dogs than normal dogs in both thoracic limbs (TL) and pelvic limbs (PL) only at day 3 after surgery. BS-TL was significantly wider in SCI-affected dogs at days 3, 10 and 30 following surgery compared to normal dogs. These findings support the use of footprint parameters to compare locomotor differences between normal and SCI-affected dogs, and to assess recovery from SCI. Additionally, our results underscore important changes in TL locomotion in thoracolumbar SCI-affected dogs.