Determination of low levels of Cd(ii) in cosmetic products by spectrophotometry after separation/preconcentration with cloud point extraction. Issue 12 (9th March 2016)

• Record Type: Journal Article
• Authors: Altunay, Nail; Gürkan, Ramazan
• Is Part Of: Analytical methods. Volume 8:Issue 12(2016)
• Page Start: 2673
• Page End: 2683
• Publication Date: 2016-03-09
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/c5ay03330f
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : In the present study, a simple, low-cost and efficient method was developed for the extraction and preconcentration of Cd(ii ) from cosmetic products by using cloud point extraction (CPE) prior to spectrophotometric detection. Abstract : In the present study, a simple, low-cost and efficient method was developed for the extraction and preconcentration of Cd(ii ) from cosmetic products by using cloud point extraction (CPE) prior to spectrophotometric detection. The method is based on the ternary complex formation of Cd(ii ) ions with 2′, 7′-dichlorofluorescein (DClF) in the presence of 2, 2′-bipyridine (Bipyr) and NaCl as chelating and salting-out agents at pH 7.0 respectively, and then their extraction into the micellar phase of polyethylene glycol tert -octylphenyl ether (Triton X-114). The effects of various variables affecting complex formation and CPE efficiency were investigated and optimized. The calibration graph was highly linear in the range of 8–120 μg L −1 with a good regression coefficient, in which the absorbance decreased with increase in the concentration of Cd(ii ) at 502 nm. The limits of detection and quantification were 2.5 and 8.3 μg L −1 with a sensitivity enhancement factor of 31.4, respectively. The relative standard deviations (RSDs) were in the range of 2.5–5.1% (for 15, 30 and 60 μg L −1, n : 5). The recovery rates of spiked samples were in the range of 97.2–103% (15, 30 and 60 μg L −1, n : 5). The accuracy of the method was determined by the analysis of a certified reference material (CRM 1548a typical diet). It has been observed that the result for Cd(ii ) is statistically within 95% confidence limit for the certified value. The results show that the proposed method can be applied satisfactorily to determine Cd(ii ) in cosmetic products.