Alstorisine A, a nor-monoterpenoid indole alkaloid from cecidogenous leaves of Alstonia scholaris. Issue 16 (20th April 2016)

• Record Type: Journal Article
• Authors: Chen, Ying-Ying; Yang, Jing; Yang, Xing-Wei; Khan, Afsar; Liu, Lu; Wang, Bei; Zhao, Yun-Li; Liu, Ya-Ping; Ding, Zhong-Tao; Luo, Xiao-Dong
• Is Part Of: Tetrahedron letters. Volume 57:Issue 16(2016)
• Page Start: 1754
• Page End: 1757
• Publication Date: 2016-04-20
• Subjects: Alstonia scholaris -- Galls -- Monoterpenoid indole alkaloid -- Absolute configuration; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2016.03.022
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: A nor -monoterpenoid indole alkaloid was isolated from A. scholaris . A plausible biogenesis of the isolated alkaloid was postulated. Alstorisine A appeared equally in galls and normal part of cecidogenous leaves. It was present at 3 μg/g as indicated by LC–MS quantitative analysis. Abstract: Alstorisine A (1 ), a novel nor -monoterpenoid indole alkaloid with 6/5/6/6 fused-ring system, regarded as a key intermediate from melodinine E to mersicarpine, was isolated from the cecidogenous leaves of Alstonia scholaris . Its structure was identified on the basis of extensive spectroscopic analysis and the comparison of experimental and calculated ECDs. A plausible biogenesis was also postulated.