Unusual sesquiterpenes from Centaurea athoa DC. (March 2016)

• Record Type: Journal Article
• Authors: Demir, Serdar; Karaalp, Canan; Bedir, Erdal
• Is Part Of: Phytochemistry letters. Volume 15(2016:Mar.)
• Page Start: 245
• Page End: 250
• Publication Date: 2016-03
• Subjects: Centaurea athoa -- Asteraceae -- Sesquiterpene -- Athoin -- 14-O-acetylathoin -- Methyl 14-O-acetylathoin-12-oate; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2016.02.012
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: Three new elemane-type sesquiterpenes were isolated from Centaura athoa DC. The isolated compounds were established by spectroscopic methods. A germacrane-type sesquiterpene is reported for the first time in the genus Centaurea . Abstract: Three new elemane-type sesquiterpenes; athoin, 14- O -acetylathoin and methyl 14- O -acetylathoin-12-oate were isolated from the aerial parts of Centaurea athoa DC., accompanying with eight known compounds: a germacrane-type sesquiterpene; 4'-hydroxypecterolide-14- O -acetate, three phenolic compounds; p -hydroxybenzoic acid, protocatechuic acid, vanillic acid-4- O -β-d -glucopyranoside methyl ester, an acetophenon glucoside; picein, two phenylpropane glucosides; syringin and 9- O -methyl coniferin, and a phytosterol; β-sitosterol-3- O -β-d -glucopyranoside. Structural elucidation of the compounds was based on both spectroscopic evidence and reference data comparison.