Cover Picture: An Efficient and Modular Route to Sequence‐Defined Polymers Appended to DNA (Angew. Chem. Int. Ed. 18/2014). Issue 18 (1st April 2014)

• Record Type: Journal Article
• Authors: Edwardson, Thomas G. W.; Carneiro, Karina M. M.; Serpell, Christopher J.; Sleiman, Hanadi F.
• Is Part Of: Angewandte Chemie international edition. Volume 53:Issue 18(2014)
• Page Start: 4497
• Page End: 4497
• Publication Date: 2014-04-01
• Subjects: amphiphiles -- DNA -- polymers -- self‐assembly -- solid‐phase synthesis; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201401123
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : Sequence‐controlled polymers attached to DNA can be prepared by solid‐phase phosphoramidite coupling, as H. F. Sleiman, C. J. Serpell, and co‐workers report in their Communication onpage 4567 ff. Polymers with the same molecular composition but different monomer patterns exhibit different amphiphilic self‐assembly. As the DNA component still retains base‐pairing fidelity, these novel conjugates encode information in two distinct, and orthogonal, assembly languages.