Click‐Chemistry Immobilized 3D‐Infused Microarrays in Nanoporous Polymer Substrates. Issue 6 (7th January 2016)

• Record Type: Journal Article
• Authors: Hirtz, Michael; Feng, Wenqian; Fuchs, Harald; Levkin, Pavel A.
• Is Part Of: Advanced materials interfaces. Volume 3:Issue 6(2016)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2016-01-07
• Subjects: 3D microarrays -- click‐chemistry -- copper(I)‐catalyzed azide‐alkyne cycloaddition -- microspotting -- polymer films; Materials science -- Periodicals; 620.11
• DOI: 10.1002/admi.201500469
• Languages: English
• ISSNs: 2196-7350

Abstract

Abstract : 3D microarrays are created in a nanoporous polymer film. The microarrays are stabilized by covalent attachment over a click‐chemistry approach and exhibit an enhanced dynamic range for the detection of antibody binding due to a higher amount of binding sites in the nanoporous film compared to flat substrates with conventional 2D surface arrays.