Incidental finding of multiple well‐differentiated papillary mesotheliomas in peritoneum. Issue 4 (14th January 2016)

• Record Type: Journal Article
• Authors: Jakobsen, Mark; Engvad, Birte; Jensen, Thor; Marcussen, Niels
• Is Part Of: Apmis. Volume 124:Issue 4(2016:Apr.)
• Page Start: 333
• Page End: 334
• Publication Date: 2016-01-14
• Subjects: Mesothelioma -- peritoneum; Pathology -- Periodicals; Microbiology -- Periodicals; Immunology -- Periodicals; 572
• DOI: 10.1111/apm.12503
• Languages: English
• ISSNs: 0903-4641

Abstract

Abstract : We present a case of multiple well‐differentiated papillary mesotheliomas (WDPM) in the peritoneum found incidentally in a 63‐year‐old man with urothelial carcinoma of the bladder. When multiple tumors are seen, malignant mesothelioma should be excluded by histopathological examination as this may have a similar focal appearance to WDPM. True stromal invasion is by far the most reliable criterion of mesothelial malignancy. In doubtful cases, a conservative diagnostic approach has been recommended. Compared to malignant mesotheliomas, WDPMs are rare and have a relatively indolent clinical course with a good prognosis. Great care is needed when diagnosing mesothelial proliferations, given the crucial nature of a benign vs malignant diagnosis. No standardized treatment has yet been established.