Longitudinal outcome and recovery of social problems after pediatric traumatic brain injury (TBI): Contribution of brain insult and family environment. Issue 49 (April 2016)

• Record Type: Journal Article
• Authors: Ryan, Nicholas P.; van Bijnen, Loeka; Catroppa, Cathy; Beauchamp, Miriam H.; Crossley, Louise; Hearps, Stephen; Anderson, Vicki
• Is Part Of: International journal of developmental neuroscience. Issue 49(2016:Apr.)
• Page Start: 23
• Page End: 30
• Publication Date: 2016-04
• Subjects: ANZSCO Australian and New Zealand Standard Classification of Occupations -- CBCL Child Behavior Check List -- GCS Glasgow Coma Scale -- MRI Magnetic Resonance Imaging -- SES Socioeconomic Status -- SWI Susceptibility-weighted Imaging -- TBI Traumatic Brain Injury; Social problems -- Pediatrics -- Brain injuries -- Magnetic resonance imaging -- Neurobiology; Developmental neurobiology -- Periodicals; Neurology -- Periodicals; Neurologie du développement -- Périodiques; Developmental neurobiology; Periodicals; 612.8
• DOI: 10.1016/j.ijdevneu.2015.12.004
• Languages: English
• ISSNs: 0736-5748

Abstract

Highlights: We evaluate longitudinal recovery of social problems (SP) post-pediatric TBI. Severe TBI was associated with significant increases in SP across time. SP were linked to corpus callosum lesions found on susceptibility-weighted imaging. Parent mental health and family function were significantly related to long-term SP. Abstract: Pediatric traumatic brain injury (TBI) can result in a range of social impairments, however longitudinal recovery is not well characterized, and clinicians are poorly equipped to identify children at risk for persisting difficulties. Using a longitudinal prospective design, this study aimed to evaluate the contribution of injury and non-injury related risk and resilience factors to longitudinal outcome and recovery of social problems from 12- to 24-months post-TBI. 78 children with TBI (injury age: 5.0–15.0 years) and 40 age and gender-matched typically developing (TD) children underwent magnetic resonance imaging including a susceptibility-weighted imaging (SWI) sequence 2–8 weeks post-injury ( M = 39.25, SD = 27.64 days). At 12 and 24-months post- injury, parents completed questionnaires rating their child's social functioning, and environmental factors including socioeconomic status, caregiver mental health and family functioning. Results revealed that longitudinal recovery profiles differed as a function of injury severity, such that among children with severe TBI, social problems significantly increased from 12- to 24-months post-injury, and were found to be significantly worse than TD controls and children with mild and moderate TBI. In contrast, children with mild and moderate injuries showed few problems at 12-months post-injury and little change over time. Pre-injury environment and SWI did not significantly contribute to outcome at 24-months, however concurrent caregiver mental health and family functioning explained a large and significant proportion of variance in these outcomes. Overall, this study shows that longitudinal recovery profiles differ as a function of injury severity, with evidence for late-emerging social problems among children with severe TBI. Poorer long-term social outcomes were associated with family dysfunction and poorer caregiver mental health at 24-months post injury, suggesting that efforts to optimize the child's environment and bolster family coping resources may enhance recovery of social problems following pediatric TBI.