Acid-promoted bicyclization of arylacetylenes to benzobicyclo[3.2.1]octanes through cationic rearrangements. Issue 24 (3rd March 2016)

• Record Type: Journal Article
• Authors: Su, Xiang; Sun, Yihua; Yao, Jiannian; Chen, Hui; Chen, Chao
• Is Part Of: Chemical communications. Volume 52:Issue 24(2016)
• Page Start: 4537
• Page End: 4540
• Publication Date: 2016-03-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc00452k
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Acid-promoted site- and stereo-selective bicyclization of alkynes to benzobicyclo[3.2.1]octanes was realized with atom- and step-economy. The reaction proceeded through two C–C bonds formed on remote alkyl C–H bonds via twice long-distance cationic rearrangement. Abstract : Acid-promoted efficient, site- and stereo-selective bicyclization of alkynes to polycyclic compounds (benzobicyclo[3.2.1]octanes) was realized with atom- and step-economy. The reaction proceeded through two C–C bonds formed on remote alkyl C–H bonds via twice long-distance cationic rearrangement.