Effect of lidocaine spray in pain management during office-based endometrial sampling: A randomised placebo-controlled trial. (17th February 2016)

• Record Type: Journal Article
• Authors: Aksoy, H.; Aksoy, U.; Ozyurt, S.; Acmaz, G.; Babayigit, M. A.; Yücel, B.; Aydin, T.
• Is Part Of: Journal of obstetrics and gynaecology. Volume 36:Number 2(2016)
• Page Start: 246
• Page End: 250
• Publication Date: 2016-02-17
• Subjects: Endometrial biopsy -- analgesia -- lidocaine spray; Obstetrics -- Periodicals; Gynecology -- Periodicals; 618.05
• DOI: 10.3109/01443615.2015.1060201
• Languages: English
• ISSNs: 0144-3615

Abstract

Abstract : Office-based endometrial sampling is the most frequently performed gynaecological procedure. The procedure is usually associated with pain and discomfort. Several anaesthetic and analgesic techniques (e.g., non-steroidal anti-inflammatory drugs, paracervical block, misoprostol and topical anaesthetics) are used for pain management during endometrial sampling. There is no comprehensive study using lidocaine in spray form; we sought to investigate the analgesic efficacy of 10% lidocaine spray in patients undergoing office-based endometrial biopsy. We conducted a prospective, randomised (lidocaine spray ( n = 60) and placebo ( n = 60), respectively), double-blind study. The mean pain score during procedure was 3.51 ± 1.51 in the lidocaine spray group and 5.11 ± 1.66 in the placebo group. Lidocaine spray treatment significantly lowered the pain scores compared with placebo ( p < 0.001). Lidocaine spray can be accepted as a non-invasive, easy to apply and more comfortable anaesthetic method for office-based endometrial sampling.