ChemInform Abstract: Multicomponent Reaction of Z‐Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One‐Pot Route to Aminodioximes and Their Transformation into 5‐Amino‐1, 2, 4‐oxadiazoles by Mitsunobu—Beckmann Rearrangement. Issue 9 (February 2016)

• Record Type: Journal Article
• Authors: Mercalli, Valentina; Massarotti, Alberto; Varese, Monica; Giustiniano, Mariateresa; Meneghetti, Fiorella; Novellino, Ettore; Tron, Gian Cesare
• Is Part Of: ChemInform. Volume 47:Issue 9(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-02
• Subjects: oxadiazole derivatives -- multicomponent reactions -- ketone derivatives (benzene compounds) -- hydroxylamine derivatives (acyclic compounds) -- ring closure reactions, annulation reactions; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201609163
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: A three‐component coupling reaction of Z‐chloro oximes, isocyanides, and hydroxylamine affords aminoglyoximes via [3+1] cycloaddition with preferential attack of isocyanides to nitrile N‐oxides.