A peptide hydrogel derived from a fragment of human cardiac troponin C. Issue 21 (19th February 2016)

• Record Type: Journal Article
• Authors: De Leon-Rodriguez, Luis M.; Kamalov, Meder; Hemar, Yacine; Mitra, Alok K.; Castelletto, Valeria; Hermida-Merino, Daniel; Hamley, Ian W.; Brimble, Margaret A.
• Is Part Of: Chemical communications. Volume 52:Issue 21(2016)
• Page Start: 4056
• Page End: 4059
• Publication Date: 2016-02-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc00209a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The human cardiac troponin C peptide fragment H-V 9 EQLTEEQKNEFKAAFDIFVLGA 31 -OH self assembles into β-sheets fibrils that further entangle to give a hydrogels. Abstract : The human cardiac troponin C peptide fragment H-V 9 EQLTEEQKNEFKAAFDIFVLGA 31 -OH, which covers helix-A in the native protein, self-assembles into β-sheet fibrils in solution. These fibrils further entangle to give a hydrogel. This peptide may therefore serve as a template for development of novel biomaterials.