The construction of functional protein nanotubes by small molecule-induced self-assembly of cricoid proteins. Issue 21 (22nd February 2016)

• Record Type: Journal Article
• Authors: Miao, Lu; Fan, Qiusheng; Zhao, Linlu; Qiao, Qinglong; Zhang, Xiyu; Hou, Chunxi; Xu, Jiayun; Luo, Quan; Liu, Junqiu
• Is Part Of: Chemical communications. Volume 52:Issue 21(2016)
• Page Start: 4092
• Page End: 4095
• Publication Date: 2016-02-22
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc00632a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Induced by small molecular ethylenediamine and "zero-length" covalent crosslinking, covalently crosslinked SeSP1 protein nanotubes with great GPx activity was fabricated. Abstract : A simple strategy has been developed to construct high-ordered protein nanotubes using electrostatic interactions and "zero-length" crosslinking induced by small molecular ethylenediamine. Furthermore, utilizing covalent crosslinking, we constructed stable nanoenzymes with multi-glutathione peroxidase (GPx) active centers on the surface of the nanotubes, which were anticipated to be ideal functional bionanomaterials.