Management of follow-up of neuroendocrine neoplasias. Issue 1 (January 2016)

• Record Type: Journal Article
• Authors: Pape, Ulrich-Frank; Maasberg, Sebastian; Jann, Henning; Pschowski, René; Krüger, Sandrine; Prasad, Vikas; Denecke, Timm; Wiedenmann, Bertram; Pascher, Andreas
• Is Part Of: Best practice & research. Volume 30:Issue 1(2016)
• Page Start: 129
• Page End: 140
• Publication Date: 2016-01
• Subjects: neuroendocrine neoplasia -- prognosis -- grading -- staging -- primary tumor -- outcome -- quality of life -- follow-up; Endocrine glands -- Diseases -- Periodicals; Metabolism -- Disorders -- Periodicals; Endocrinology -- Periodicals; Metabolism -- Periodicals; 616.4
• DOI: 10.1016/j.beem.2016.02.001
• Languages: English
• ISSNs: 1521-690X

Abstract

Abstract : Neuroendocrine neoplasias (NEN) comprise heterogeneous epithelial neoplasms with a large variety of clinical presentations, treatment options and outcomes. Since potentially all NEN bear malignant potential it is important for long-term clinical management and improvement of outcome to decide on successful and oncologically and economically meaningful follow-up strategies. Evidence-based outcome data validating specific follow-up strategies are, however, not available to date and thus outcome data, known prognostic factors and clinical experience guide the decisions on follow-up regimens. The review summarizes general recommendations as well as specific considerations based on tumor entities, clinicopathological tumor characteristics and clinical experience. Follow-up shall serve the patient to improve outcome, benefit from more effective therapies and suffer less from unnecessary and/or toxic therapeutic interventions and finally preserve or gain a good quality of life.