A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model. Issue 11 (4th January 2016)
- Record Type:
- Journal Article
- Title:
- A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model. Issue 11 (4th January 2016)
- Main Title:
- A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model
- Authors:
- Liu, Yaping
Ma, Huilong
Zhang, Liangwei
Cui, Yajing
Liu, Xiaoting
Fang, Jianguo - Abstract:
- Abstract : The first off–on probe, Mito-TRFS, for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells was reported. Abstract : The first off–on probe, Mito-TRFS, for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells was reported. In a cellular model of Parkinson's disease (PD), Mito-TRFS staining discloses a drastic decline of the TrxR2 activity, providing a mechanistic link of TrxR2 dysfunction to the etiology of PD.
- Is Part Of:
- Chemical communications. Volume 52:Issue 11(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 11(2016)
- Issue Display:
- Volume 52, Issue 11 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 11
- Issue Sort Value:
- 2016-0052-0011-0000
- Page Start:
- 2296
- Page End:
- 2299
- Publication Date:
- 2016-01-04
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c5cc09998f ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1316.xml