A leucine zipper pair-based lipid vesicle for image-guided therapy in breast cancer. Issue 13 (11th January 2016)

• Record Type: Journal Article
• Authors: Lim, Eun-Kyung; Bae, Panki; Kim, Haeran; Jung, Juyeon
• Is Part Of: Chemical communications. Volume 52:Issue 13(2016)
• Page Start: 2687
• Page End: 2690
• Publication Date: 2016-01-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc08659k
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : We developed a controllable image-guided therapy system as a powerful tool for diagnostic and therapeutic applications. Abstract : We developed a controllable image-guided therapy system as a powerful tool for diagnostic and therapeutic applications. The system uses a two-step pretargeting approach that takes advantage of the highly selective binding interactions between leucine zipper pairs. It consists of the utilization of a tumor pretargeting probe for diagnosis and, if necessary, a probe for therapy.