An unexpected metal-free DMAP catalyzed Michael addition–elimination domino reaction between 2-naphthols and bromomaleimides for the effective construction of 3-arylmaleimides. Issue 11 (16th March 2016)

• Record Type: Journal Article
• Authors: Zhang, Yong; Chen, Feng; Yang, Yu; Tang, Chao-Zhe; Tian, Fang; Peng, Lin; Wang, Li-Xin
• Is Part Of: Tetrahedron letters. Volume 57:Issue 11(2016)
• Page Start: 1261
• Page End: 1264
• Publication Date: 2016-03-16
• Subjects: Metal-free catalysis -- Domino reaction -- 2-Naphthol -- Bromomaleimide -- 3-Arylmaleimide; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2016.02.016
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: An unexpected novel DMAP catalyzed Michael addition–elimination domino reaction between 2-naphthols and bromomaleimides has been reported. This protocol features metal-free catalysis and mild reaction conditions, which furnished 3-aryl maleimides in moderate to excellent yields (25–89% yields). Abstract: An unexpected novel DMAP catalyzed Michael addition–elimination domino reaction between 2-naphthols and bromomaleimides has been reported. This protocol features metal-free catalysis and mild reaction conditions, which furnished 3-arylmaleimides in moderate to excellent yields (25–89% yields).