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ChemInform Abstract: Benefits of a Dual Chemical and Physical Activation: Direct Aza‐Michael Addition of Anilines Promoted by Solvent Effect under High Pressure. Issue 10 (February 2016)
Record Type:
Journal Article
Title:
ChemInform Abstract: Benefits of a Dual Chemical and Physical Activation: Direct Aza‐Michael Addition of Anilines Promoted by Solvent Effect under High Pressure. Issue 10 (February 2016)
Main Title:
ChemInform Abstract: Benefits of a Dual Chemical and Physical Activation: Direct Aza‐Michael Addition of Anilines Promoted by Solvent Effect under High Pressure.
Abstract: The combination of hexafluoroisopropanol as solvent and high‐pressure conditions enables the unprecedented 1, 4‐addition of poor nucleophiles like aromatic amines onto sluggish Michael acceptors without a promoter or work‐up.