DABCO-catalyzed consecutive one pot four-component protocol for the synthesis of a novel class of (Z)-5-(3-hydroxy-2-oxoindolin-3-yl)-2-iminothiazolidin-4-ones. Issue 17 (2nd February 2016)

• Record Type: Journal Article
• Authors: Bejjam, Madhu Babu; Kumar, G. Santhosh; Swetha, A.; Meshram, H. M.
• Is Part Of: RSC advances. Volume 6:Issue 17(2016)
• Page Start: 13820
• Page End: 13828
• Publication Date: 2016-02-02
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra24127h
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A DABCO catalyzed, novel and efficient one-pot, four component protocol has been developed for the synthesis of ( Z )-5-(3-hydroxy-2-oxoindolin-3-yl)-2-iminothiazolidin-4-one scaffolds under metal-free conditions. Abstract : A DABCO catalyzed, novel and efficient one-pot, four component protocol has been developed for the synthesis of ( Z )-5-(3-hydroxy-2-oxoindolin-3-yl)-2-iminothiazolidin-4-one scaffolds under metal-free conditions. By virtue of simple and readily available starting materials, mild reaction conditions, and the high bioactivity of oxindole derivatives, this reaction promises diverse applications in medical chemistry.