A simple analytical model for signal amplification by reversible exchange (SABRE) process. Issue 1 (8th December 2015)

• Record Type: Journal Article
• Authors: Barskiy, Danila A.; Pravdivtsev, Andrey N.; Ivanov, Konstantin L.; Kovtunov, Kirill V.; Koptyug, Igor V.
• Is Part Of: Physical chemistry chemical physics. Volume 18:Issue 1(2016)
• Page Start: 89
• Page End: 93
• Publication Date: 2015-12-08
• Subjects: Chemistry, Physical and theoretical -- Periodicals; 541.3
• DOI: 10.1039/c5cp05134g
• Languages: English
• ISSNs: 1463-9076

Abstract

Abstract : An analytical model was derived for signal amplification by reversible exchange (SABRE) process based on the combined analysis of chemical kinetics and the evolution of a nuclear spin ensemble. Abstract : We demonstrate an analytical model for the description of the signal amplification by reversible exchange (SABRE) process. The model relies on a combined analysis of chemical kinetics and the evolution of the nuclear spin system during the hyperpolarization process. The presented model for the first time provides rationale for deciding which system parameters ( i.e. J -couplings, relaxation rates, reaction rate constants) have to be optimized in order to achieve higher signal enhancement for a substrate of interest in SABRE experiments.