Solvent effect in β-phosphorylated nitroxides. Part 4: detection of traces of water by electron paramagnetic resonance. Issue 4 (9th December 2015)

• Record Type: Journal Article
• Authors: Audran, Gérard; Bosco, Lionel; Brémond, Paul; Butscher, Teddy; Marque, Sylvain R. A.
• Is Part Of: Organic & biomolecular chemistry. Volume 14:Issue 4(2016)
• Page Start: 1288
• Page End: 1292
• Publication Date: 2015-12-09
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob02316e
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Detection by EPR of traces (0.1%) of water in polar solvent such as THF. Abstract : For decades, the nitrogene hyperfine coupling constant a N of nitroxides has been applied to probe their environment using EPR. However, the small changes observed (≈2 G from n -pentane to water) with the solvent polarity allow only a qualitative discussion. A stable β-phosphorylated nitroxide exhibiting a small change in a N (≈3 G from n -pentane to water) and a striking change (≈25 G from n -pentane to water) in phosphorus hyperfine coupling constant a P with the polarity of solvent was prepared and used to develop the first procedure for the titration of water in THF by EPR, down to 0.1% v/v.