Zn/Sc bimetallic relay catalysis: one pot cycloisomerization/carbonyl–ene reaction toward oxazole derivatives. Issue 3 (26th November 2015)

• Record Type: Journal Article
• Authors: Wang, Bin; Chen, Ying; Zhou, Ling; Wang, Jianwu; Xu, Zhenghu
• Is Part Of: Organic & biomolecular chemistry. Volume 14:Issue 3(2016)
• Page Start: 826
• Page End: 829
• Publication Date: 2015-11-26
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob02158h
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A novel tandem metal relay catalytic system combining Zn(ii )-catalyzed cycloisomerization and a Sc(iii )-catalyzed carbonyl–ene reaction has been successfully developed. Abstract : A novel tandem metal relay catalytic system combining Zn(ii )-catalyzed cycloisomerization and a Sc(iii )-catalyzed carbonyl–ene reaction has been successfully developed. By using this unprecedented Zn/Sc bimetallic relay catalytic system, a variety of oxazole derivatives were obtained from easily available N -(propargyl)arylamides and aldehydes under mild conditions.