Assemblies of ionic zinc chlorins assisted by water-soluble polypeptides. Issue 5 (1st March 2016)

• Record Type: Journal Article
• Authors: Miyatake, Tomohiro; Hasunuma, Yuki; Mukai, Yumi; Oki, Hisato; Watanabe, Mikiya; Yamazaki, Shohei
• Is Part Of: Bioorganic & medicinal chemistry. Volume 24:Issue 5(2016)
• Page Start: 1155
• Page End: 1161
• Publication Date: 2016-03-01
• Subjects: AN acetonitrile -- AVG average -- EDC 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide -- DMAP N, N-dimethyl-4-aminopyridine -- TEA triethylamine -- TFA trifluoroacetic acid -- LH light-harvesting -- RC reaction center -- Chl chlorophyll -- BChl bacteriochlorophyll -- THF tetrahydrofuran -- DLS dynamic light scattering -- CD circular dichroism -- HRMS high resolution mass spectrum -- MeOH methanol -- NIR near-infrared -- pAsp poly-l-aspartic acid -- pGlu poly-l-glutamic acid -- pLys poly-l-lysine -- pAla poly-l-alanine -- fwhm full width at half maximum; Chlorophylls -- Polypeptides -- Self-aggregation -- Light-harvesting antenna -- Reaction center -- Circular dichroism; Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; Biochemistry -- Periodicals; Chemistry, Clinical -- Periodicals; Chemistry, Organic -- Periodicals; Chimie bio-organique -- Périodiques; Chimie pharmaceutique -- Périodiques; 615.19
• DOI: 10.1016/j.bmc.2016.01.054
• Languages: English
• ISSNs: 0968-0896

Abstract

Graphical abstract: Abstract: Artificial chlorophyll–peptide complexes were prepared by mixing ionic chlorophyll derivatives and oligopeptides in aqueous media containing a small amount of organic solvent. The pigment–peptide complexes provided chlorophyll assemblies showing a sharp red-shifted Qy absorption band concomitant with giant circular dichroism signals. The polypeptide-assisted assemblies of chlorophyllous pigments would afford a good model for photosynthetic apparatuses such as pigment–protein complexes of light-harvesting antennas.