A Ru(iii) – catalyzed α-cross-coupling aldol type addition reaction of activated olefins with isatins. Issue 3 (24th December 2015)

• Record Type: Journal Article
• Authors: Kumar, A. Sanjeeva; Ramesh, Palakuri; Kumar, G. Santosh; Swetha, A.; Nanubolu, Jagadeesh Babu; Meshram, H. M.
• Is Part Of: RSC advances. Volume 6:Issue 3(2016)
• Page Start: 1705
• Page End: 1709
• Publication Date: 2015-12-24
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra14714j
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A α-cross-coupling aldol type addition reaction activated olefins with isatins has been described in the presence of ruthenium(iii ) chloride and tributyltin hydride (TBTH) at room temperature. Abstract : A α-cross-coupling aldol type addition reaction activated olefins with isatins has been described in the presence of ruthenium(iii ) chloride and tributyltin hydride (TBTH) at room temperature. This method is found to work consistently for the delivering of ene-carbonyl coupled products in good to excellent yields with moderate to acceptable selectivity. The substrate scope of the present method was briefly discussed.