Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex. Issue 9 (15th December 2015)

• Record Type: Journal Article
• Authors: Chakraborty, Subrata; Leitus, Gregory; Milstein, David
• Is Part Of: Chemical communications. Volume 52:Issue 9(2016)
• Page Start: 1812
• Page End: 1815
• Publication Date: 2015-12-15
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc08204h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A novel complex based on earth-abundant iron, and its application in the catalytic homogeneous hydrogenation of (hetero)aromatic, benzylic, and aliphatic nitriles to selectively form primary amines is discovered. Abstract : Hydrogenation of nitriles to primary amines constitutes an atom-efficient and environmentally benign synthetic reaction. Herein we present a novel complex based on earth-abundant iron, and its application in the catalytic homogeneous hydrogenation of (hetero)aromatic, benzylic, and aliphatic nitriles to selectively form primary amines.