Azeotropic drying free [18F]FDG synthesis and its application to a lab-on-chip platform. Issue 4 (12th November 2015)

• Record Type: Journal Article
• Authors: Lindner, S.; Rensch, C.; Neubaur, S.; Neumeier, M.; Salvamoser, R.; Samper, V.; Bartenstein, P.
• Is Part Of: Chemical communications. Volume 52:Issue 4(2016)
• Page Start: 729
• Page End: 732
• Publication Date: 2015-11-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc07106b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : [ 18 F]FDG was prepared using a cartridge-based drying technique for [ 18 F]fluoride. The application to a lab-on-chip platform demonstrates a proof of concept towards reduced hardware complexity. Abstract : A very simple and time-saving cartridge-based drying technique for [ 18 F]fluoride allows for an efficient [ 18 F]FDG synthesis using protic solvents and high water content. This novel method has been adapted to a lab-on-chip synthesis platform mitigating the standard azeotropic drying process and demonstrating a proof of concept towards reduced hardware complexity for such systems.