The existence of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA in mammals. Issue 4 (12th November 2015)
- Record Type:
- Journal Article
- Title:
- The existence of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA in mammals. Issue 4 (12th November 2015)
- Main Title:
- The existence of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA in mammals
- Authors:
- Zhang, Hao-Ying
Xiong, Jun
Qi, Bao-Ling
Feng, Yu-Qi
Yuan, Bi-Feng - Abstract:
- Abstract : We developed a novel strategy by oxidation–derivatization combined mass spectrometry analysis for the determination of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA. Abstract : We developed a novel strategy by oxidation–derivatization combined mass spectrometry analysis for the determination of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA. We reported the presence of 5-formylcytosine in RNA of mammals and found that ascorbic acid and hydroquinone can increase the oxidation of 5-methylcytosine to 5-hydroxymethylcytosine in DNA and RNA.
- Is Part Of:
- Chemical communications. Volume 52:Issue 4(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 4(2016)
- Issue Display:
- Volume 52, Issue 4 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 4
- Issue Sort Value:
- 2016-0052-0004-0000
- Page Start:
- 737
- Page End:
- 740
- Publication Date:
- 2015-11-12
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c5cc07354e ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 893.xml