2259 Tremelimumab - A monoclonal antibody against CTLA-4 - in combination with local tumor ablation (TACE or RFA) in patients with hepatocellular carcinoma (HCC). (September 2015) - Greten, T.; Duffy, A.; Rusher, O.; Kerkar, S.; Kleiner, D.; Figg, W.; Steinberg, S.; Abi-Jaoudeh, N.; Wood, B.