1522 X-TREME: Interim analysis from a German open-label, observational non-interventional study for treatment persistence with denosumab in routine use in adults with bone metastases secondary to solid tumours. (September 2015) - Diel, I.J.; Hecker, D.; Hesse, T.; Kluike, C.; Nusch, A.; Rohrberg, R.; Kurbacher, C.; Rueckinger, S.; Schilling, J.; Schulz, H.