340 A phase I study of the smoothened (SMO) antagonist LDE225 in combination with paclitaxel in patients with advanced solid tumors. (September 2015) - Stathis, A.; Hess, D.; Xyrafas, A.; Enoiu, M.; Berardi, S.; Moos, R. Von; Homicsko, K.; Griguolo, G.; Jörger, M.; Mark, M.; Ackermann, C.; Sessa, C.