3119 P53 disruptive mutation is a negative predictive factor in EGFR M+ NSCLC treated with TKI. (September 2015) - Lüers, A.; Neemann, N.; Prenzel, R.; Scriba, D.; Willborn, K.; Stropiep, U.; Falk, M.; Hallas, C.; Tiemann, M.; Griesinger, F.