Sleep disorders and respiratory function in amyotrophic lateral sclerosis. (April 2016)

• Record Type: Journal Article
• Authors: Ahmed, Rebekah M.; Newcombe, Rowena E.A.; Piper, Amanda J.; Lewis, Simon J.; Yee, Brendon J.; Kiernan, Matthew C.; Grunstein, Ron R.
• Is Part Of: Sleep medicine reviews. Volume 26(2016)
• Page Start: 33
• Page End: 42
• Publication Date: 2016-04
• Subjects: Amyotrophic lateral sclerosis -- Sleep -- Respiratory -- Ventilation; ALS amyotrophic lateral sclerosis -- CPAP continuous positive airway pressure -- OSA obstructive sleep apnea -- SDB sleep disordered breathing; Sleep disorders -- Periodicals; Sleep Disorders -- Periodicals; Sommeil, Troubles du -- Périodiques; Electronic journals; 616.8498
• DOI: 10.1016/j.smrv.2015.05.007
• Languages: English
• ISSNs: 1087-0792

Abstract

Summary: Sleep disorders in amyotrophic lateral sclerosis (ALS) present a significant challenge to the management of patients. Issues include the maintenance of adequate ventilatory status through techniques such as non-invasive ventilation, which has the ability to modulate survival and improve patient quality of life. Here, a multidisciplinary approach to the management of these disorders is reviewed, from concepts about the underlying neurobiological basis, through to current management approaches and future directions for research.