Hemorrhage in astroblastoma: An unusual manifestation of an extremely rare entity. (March 2016)

• Record Type: Journal Article
• Authors: Singla, Navneet; Dhandapani, S.S.; Kapoor, Ankur; Chatterjee, Debajyoti; Vashishta, R.K.
• Is Part Of: Journal of clinical neuroscience. Volume 25(2016:Mar.)
• Page Start: 147
• Page End: 150
• Publication Date: 2016-03
• Subjects: Astroblastoma -- Anaplastic -- Hemorrhage; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2015.05.058
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: Hemorrhage in astroblastoma is a rare phenomena. We present two cases of this and emphasize early suspicion in superficially located lesions. Astroblastoma can be low grade or anaplastic. We present one patient of each type and discuss the natural history. Histology and extent of excision remain the predictors of recurrence. Abstract: Astroblastoma is a rare tumor of glial origin with characteristics of both astrocytoma and ependymoma. It is usually seen in children and young adults, and is peripherally located, well circumscribed, of solid-cystic composition and with heterogeneous contrast enhancement. Histopathology reveals perivascular pseudorosette formation and thick hyalinised vessels. Hemorrhage in astroblastoma is unusual and rarely described in literature. We report two patients with astroblastoma who presented with hemorrhage and discuss the natural history, radiological findings, pathophysiology of hemorrhage and histopathological characteristics. We emphasize the importance of early suspicion in peripherally located lesions with bleeding.