Highly selective, sensitive and fluorescent sensing of dimeric G-quadruplexes by a dimeric berberine. Issue 1 (18th November 2015)

• Record Type: Journal Article
• Authors: Zhou, Chun-Qiong; Yang, Jian-Wei; Dong, Cheng; Wang, Yong-Min; Sun, Bin; Chen, Jin-Xiang; Xu, Ya-Shi; Chen, Wen-Hua
• Is Part Of: Organic & biomolecular chemistry. Volume 14:Issue 1(2016)
• Page Start: 191
• Page End: 197
• Publication Date: 2015-11-18
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob01723h
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : This paper describes the highly selective, sensitive and topology-specific fluorescent sensing of dimeric G-quadruplexes by a polyether-tethered dimeric berberine. Abstract : This paper describes the highly selective, sensitive and topology-specific fluorescent sensing of dimeric G-quadruplexes by a polyether-tethered dimeric berberine1 . Compound1 displays high selectivity for dimeric G-quadruplexes over monomeric ones, and can be lit up by dimeric G-quadruplexes, in particular by the one linked with one TTA subunit. In addition, it shows no effect on the topology or thermal stability of the G-quadruplexes.