Alkenes with antioxidative activities from Murraya koenigii (L.) Spreng. Issue 3 (1st February 2016)

• Record Type: Journal Article
• Authors: Ma, Qin-Ge; Xu, Kun; Sang, Zhi-Pei; Wei, Rong-Rui; Liu, Wen-Min; Su, Ya-Lun; Yang, Jian-Bo; Wang, Ai-Guo; Ji, Teng-Fei; Li, Lu-Jun
• Is Part Of: Bioorganic & medicinal chemistry letters. Volume 26:Issue 3(2016)
• Page Start: 799
• Page End: 803
• Publication Date: 2016-02-01
• Subjects: Murraya koenigii -- Alkene -- Antioxidative activity; Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1016/j.bmcl.2015.12.091
• Languages: English
• ISSNs: 0960-894X

Abstract

Graphical abstract: Abstract: Four new alkenes (1 –4 ), and six known alkenes (5 –12 ) were isolated from Murraya koenigii (L.) Spreng. Their structures were elucidated on the basis of spectroscopic analyses and references. Compounds (1 –12 ) were evaluated for antioxidative activities. Among them, compounds1, 2, 4, and7 exhibited significant antioxidative activities using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay with IC50 = 21.4–49.5 μM. The known compounds (5 –12 ) were isolated from this plant for the first time.