Polycyclic tetrahydroxanthones from Streptomyces chrestomyceticus BCC 24770. Issue 5 (4th February 2016)

• Record Type: Journal Article
• Authors: Bunyapaiboonsri, Taridaporn; Lapanun, Sanisa; Supothina, Sumalee; Rachtawee, Pranee; Chunhametha, Suwanee; Suriyachadkun, Chanwit; Boonruangprapa, Tanapong; Auncharoen, Patchanee; Chutrakul, Chanikul; Vichai, Vanicha
• Is Part Of: Tetrahedron. Volume 72:Issue 5(2016)
• Page Start: 775
• Page End: 778
• Publication Date: 2016-02-04
• Subjects: Antifungal activity -- Streptomyces chrestomyceticus -- Polycyclic tetrahydroxanthone -- Secondary metabolite; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2015.12.045
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: Three polycyclic tetrahydroxanthones, chrestoxanthones A−C, together with known albofungin and chloroalbofungin were isolated from the actinomycete Streptomyces chrestomyceticus BCC 24770. Their structures were elucidated by extensive spectroscopic analyses. Chrestoxanthone A was active against Curvularia lunata and Alternaria brassicicola, while all other isolated metabolites displayed broad antifungal activities against C. lunata, A. brassicicola, Colletotrichum capsici, and Colletotrichum gloeosporioides. Graphical abstract: