A supramolecular hydrogel for generation of a benign DNA-hydrogel. Issue 128 (14th December 2015)

• Record Type: Journal Article
• Authors: Dey, B.; Mondal, R. K.; Mukherjee, S.; Satpati, B.; Mukherjee, N.; Mandal, A.; Senapati, D.; Sinha Babu, S. P.
• Is Part Of: RSC advances. Volume 5:Issue 128(2015)
• Page Start: 105961
• Page End: 105968
• Publication Date: 2015-12-14
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra19172f
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A DNA-hydrogel, produced using calf-thymus DNA and a 2′, 4′, 6′-tri(4-pyridyl)pyridine based luminescent supramolecular hydrogel, can stabilize sunray mediated photochemically synthesized bio-compatible, luminous Ag-NPs. Abstract : A novel hydrogel has been synthesized using 2′, 4′, 6′-tri(4-pyridyl)pyridine in an acidic water medium. TEM analyses along with rheological experiments explore the supramolecular features of the hydrogel. In vitro and in vivo toxicity studies depict the non-toxic and bio-relevant nature of the pure supramolecular hydrogel and its aqueous solution. This bio-compatible supramolecular hydrogel is used for the synthesis of a DNA-hydrogel with calf thymus DNA. The DNA-hydrogel is intriguing for the effective stabilization of photochemically synthesized silver nanoparticles from Ag(i ) under the direct exposure of sunrays. DNA-hydrogel capped Ag-NPs are also bio-compatible. The luminous features of the 2′, 4′, 6′-tri(4-pyridyl)pyridine based supramolecular hydrogel, DNA-hydrogel and DNA-hydrogel capped Ag-NPs and their aqueous solutions are explored through fluorescence microscopy and spectral analyses, respectively.