Bilateral glossopharyngeal neuropathy following chemo and radiation therapy for a primitive neuroectodermal tumour. (14th November 2015)

• Record Type: Journal Article
• Authors: Heir, G. M.; Masterson, M.
• Is Part Of: Journal of oral rehabilitation. Volume 43:Number 2(2016:Feb.)
• Page Start: 154
• Page End: 158
• Publication Date: 2015-11-14
• Subjects: glossopharyngeal nerve -- neuroecto‐dermal tumour‐primitive -- chemotherapy -- temporomandibular joint -- otitis media -- pain; Dentistry -- Periodicals; Prosthodontics -- Periodicals; 617
• DOI: 10.1111/joor.12347
• Languages: English
• ISSNs: 0305-182X

Abstract

Summary: This case describes a young adult male patient diagnosed and treated for a primitive neuroectodermal tumour (PNET) at 3 years of age. Chemotherapy and radiation therapy used following surgical treatment of this tumour have known neurotoxic complications, some of which have delayed onset. In this case, the patient exhibited sudden onset, persistent bilateral and deep ear pain that was consistent with a neuropathy of the glossopharyngeal nerve occurring 17 years after the completion of therapy for PNET. Treatment with pregabalin was successful with near‐complete resolution of the complaint. The diagnostic certainty in this case is discussed in relation to the current diagnostic criteria for neuropathic pain.