Enhancing the efficacy of cation-independent mannose 6-phosphate receptor inhibitors by intracellular delivery. Issue 2 (30th October 2015)

• Record Type: Journal Article
• Authors: Agarwal, Vipul; Toshniwal, Priyanka; Smith, Natalie E.; Smith, Nicole M.; Li, Binbin; Clemons, Tristan D.; Byrne, Lindsay T.; Kakulas, Foteini; Wood, Fiona M.; Fear, Mark; Corry, Ben; Swaminathan Iyer, K.
• Is Part Of: Chemical communications. Volume 52:Issue 2(2016)
• Page Start: 327
• Page End: 330
• Publication Date: 2015-10-30
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc06826f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Intracellular delivery of M6P/IGFII receptor inhibitors exhibits better efficacy than extracellular inhibitors to regulate TGFβ1 mediated upregulation of profibrotic marker, collagen I. Abstract : Intracellular delivery of M6P/IGFII receptor inhibitors exhibits better efficacy than extracellular inhibitors to regulate TGFβ1 mediated upregulation of profibrotic marker, collagen I.