Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation. Issue 3 (9th November 2015)

• Record Type: Journal Article
• Authors: Liang, Kang; Coghlan, Campbell J.; Bell, Stephen G.; Doonan, Christian; Falcaro, Paolo
• Is Part Of: Chemical communications. Volume 52:Issue 3(2016)
• Page Start: 473
• Page End: 476
• Publication Date: 2015-11-09
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc07577g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Recent studies have demonstrated that metal–organic frameworks can be employed as protective coatings for enzymes. Abstract : Recent studies have demonstrated that metal–organic frameworks can be employed as protective coatings for enzymes. Two efficient strategies have been reported for the synthesis of such composite materials: biomimetic mineralisation and controlled co-precipitation using polyvinylpyrrolidone. We assessed the relative efficacy of each approach by comparing the thermal stability of encapsulated urease. The resulting data shows that over a range of temperatures biomimetic mineralisation offers superior protection than the co-precipitation method.